Allison Stuart felt scared during the day she spent at the hospital in New Orleans awaiting surgery for recurring ear infections. Most 7-year-olds would. She had some things to comfort her, though - not reassuring words from her doctor or the prospect of a new treatment, but far simpler gifts: a colorful quilt and a heart-shaped pillow.

The gifts were the brainchild of entrepreneur Lisa Honig Buksbaum. In 2001, Buksbaum closed her marketing firm, Boxtree Communications (Buksbaum means “boxtree” in Yiddish), which boasted a roster of brands such as Colgate and Lipton, to launch Soaringwords, a New York City nonprofit that helps sick children and their families.

Buksbaum, 46, understands from experience the need for this type of support: Within a span of ten months in 1998, her 35-year-old brother died suddenly of an asthma-induced heart attack, her father had a recurrence of non-Hodgkin’s lymphoma (he defied the odds and survived) and her 9-year-old son became gravely ill with rheumatic fever, which left him bedridden for four months. “Everyone wants to do something positive, but they don’t know what to do to help,” she says.

Since its founding in 2001, Soaringwords has boosted the spirits of more than 150,000 pediatric patients in the U.S. and, through its Web site, reached children as far away as China, Israel, Mexico and Russia.

CNN Money